The Single Nucleotide Polymorphism rs2305957 is not Associated with Recurrent Pregnancy Loss
Authors
Abstract:
This study was conducted in order to investigate the association between the single nucleotide polymorphism (SNP) rs2305957 G/A and recurrent pregnancy loss (RPL) in a group of Palestinian women residing in Gaza strip. A retrospective case-control study was carried out during the period of May to August 2015. A total of 380 females including 190 recurrent pregnancy loss (RPL) patients and 190 control women without previous history of RPL, aged 20–35 years were included in the study. The SNP was analyzed by tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR). No statistically significant difference was found between RPL cases and controls in terms of allelic and genotypic distribution of rs2305957 G/A. SNP rs2305957 G/A does not represent a risk factor for RPL in the investigated population.
similar resources
the single nucleotide polymorphism rs2305957 is not associated with recurrent pregnancy loss
this study was conducted in order to investigate the association between the single nucleotide polymorphism (snp) rs2305957 g/a and recurrent pregnancy loss (rpl) in a group of palestinian women residing in gaza strip. a retrospective case-control study was carried out during the period of may to august 2015. a total of 380 females including 190 recurrent pregnancy loss (rpl) patients and 190 c...
full textThe single nucleotide polymorphism of DMRT1 is associated with oligospermia
Male infertility is a common human reproductive defect that can be resulted from spermatogenesis impairment. DMRT1 encodes a male-specific transcriptional regulator and is important for human spermatogenesis. This study was designed to explore the relationship between the Single Nucleotide Polymorphism (SNP) of DMRT1 and oligospermia. Two SNPs namely rs3739583 and rs4742608, were screened in 21...
full textO-7: Y Chromosome Microdeletions Are Not Associated with Spontaneous Recurrent Pregnancy Loss in A Sinhalese Population in Sri Lanka
Background: Many advances have been made in reproductive medicine yet the spontaneous loss of a pregnancy remains the most common complication of pregnancy. The aetiology of spontaneous recurrent pregnancy loss (RPL) is multifactorial. Y chromosome microdeletions are found in approximately 7% of men with low sperm counts and, compared to the general population, a higher frequency of spontaneous...
full textthe association between single nucleotide polymorphism in interleukin-27 gene and recurrent pregnancy loss in iranian women
background: recurrent pregnancy loss (rpl) has been defined as two or more miscarriages before 20 th week of gestation. it seems that il-27 may reduce inflammatory responses and affect the survival of the embryo during human pregnancy. il-27 polymorphisms may influence rpl by altering the levels or the activity of gene product. objective: we studied for the first time the association of il-27 -...
full textCYP4F2 gene single nucleotide polymorphism is associated with ischemic stroke.
The objective of this study was to explore the relationship between CYP4F2 gene polymorphism and ischemic stroke (IS) in the Han Chinese population. We performed a case-control study to genotype four single nucleotide polymorphisms (SNPs) (rs2108622, rs3093100, rs3093105, rs3093135) in the CYF4F2 gene. The genotype and haplotype distributions were compared between the case and control groups. W...
full textAssociation Of rs16260 Polymorphism Of CDH1 Gene With Recurrent Pregnancy Loss In Iranian-Azeri Women
Background & aim: Recurrent pregnancy loss is defined as loosing at least 2 pregnancies before 20th weeks of gestation. Besides all the known causative factors, in about half of the cases, the causing factor, remains unknown. In recent years, some studies have shown the role of candidate genes polymorphisms in RPL. CDH1 is one of these candidate genes that plays critical role in embryo implanta...
full textMy Resources
Journal title
volume 1 issue None
pages 81- 83
publication date 2015-06
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023